Originally Posted by szokol
There is no way to pause the game at any time. If doorbell rings, or anything distracts you, there is only hope you won't find you avatar dead (and reborn at a rebirth statue, probably far from where you left her/him) when return to the game.

It's even funnier, if you play in hardcore mode, there is no reborn, so if you die, you can start from the start.