I absolutely hate games that don't allow you to see 90-100% of the content in one playthrough. I rarely play a non-sandbox game more than once. If a game boasts a lot of replayability because you can't see everything with one character, I stay away. Even a great game, I'll typically play the same type of character over and over with minor variations. I've played my favorite game, Oblivion, multiple times but I've never done the Dark Brotherhood quests. Why? I don't play evil. I don't murder. I rarely steal. I would never play a game where I'm the anti-hero. It's not in my makeup.