Originally Posted by Wulf 
…and your mainboard cpu is….?….
Yes, I should've posted more thorough specs in my previous post. My bad. (Blame it on posting in a hurry from work. "I was working hard/hardly working…"

)
I've got an Intel i7 860 quad core processor on ASUS P7P55D-E motherboard. My OS is Windows 7 Home Premium 32-bit and I've got an ATI 5850 graphics card.
I had a similar problem with Gothic 2 on this PC, but for G2 there's the fan-made Gothic Starter thingy that fixed this launching problem. Unfortunately I cannot find anything similar for G1.
I fiddled with Gothic 1 yesterday evening a bit, like disabling virus scanners and whatnot, but still couldn't get it to launch without that Task Manager trick. How come this "rundll32.exe" is blocking G1?
P.S. I got the videos to work by disabling video scaling, as I expected.