Originally Posted by Drithius 
Approximately 200,000 actually. And 99% of that without our current ability to destroy ourselves through various means. In my opinion, if we do die off, it will likely be through a plague. And the universe will happily continue on.
Bingo, 20th and 21st century weaponry and technology paired with human impulse, greed, pride and stupidity is a helluva mixture.
Also, you make a good point with your plague spin… Regardless of whether it is a naturally occurring event or man made, our globalized environment almost guarantees all would be affected by it.