Originally Posted by rune_74 
No, I think if people don't try to use it as a mouse interface, and instead think of it as a extension of keyboard commands you may see it is pretty quick to use.
Well, a few days ago I finished Gothic 1 and I'm about 3/4s way through G2 NotR and both games make heavy use of a keyboard driven interface. So I should be well-practiced for Skyrim then.