Originally Posted by Peter Stauffenberg 
Mainly we will miss the cleric radiant aura so we will have to depend on potions for remove disease, remove curse, neutralize poison, restoration etc. Eventually the favored soul can deal with some of these and the paladin can deal with remove disease.
The ranger gets several of those spells. I think the bard does, as well. It probably still makes sense to stock up on pots, but we're not locked in.