I voted for realism as well. I also prefer if the game makes it so loot hoarding is not nessacary. The gold box games would be a good example of this. You might keep a few magical weapons for sale purposes but everything else you just disregard.
Originally Posted by BillSeurer 
The only one I dislike is the "fixed space" system like in Baldur's Gate. You can carry 55,000 pounds as long as it is small enough.
Edit: Opps I see JDR already pointed this out - so ignore this post.
Are you sure you are talking about Baldurs Gate? Carrying in Baldurs Gate is based on standard D&D 2nd edition rules. The higher your strength then the more you can carry. Someone with strength 7 would struggle to carry a single piece of plate armour.