It might seem counterintuitive, but that minigame is actually much easier with a Xbox 360 controller. The targets move a lot slower when you switch to gamepad mode, and even the accuracy of aiming with a mouse doesn't compensate for how fast they move in comparison.

I have a question - is there a pistol trainer anywhere in the Sword Coast, for the voodoo path? I found someone who sells pistols in Puerto Isabella but he doesn't offer any training. I really want the 'Nuff Said' skill.