Originally Posted by Zloth 
Honestly, it's been rough going. I'm not so sure I should have put that resolution patch in there to play at 1080p - the text and characters are so small I'm leaning forward to see.
I'd use a widescreen resolution that's closest to the original maximum that is supported by your monitor — for me that was 1280x800. Higher than original resolutions for 2D games IMO only make sense with proper upscaling algorithms like you have in emulators.