Originally Posted by Maylander
That's impossible given the ending of ME3. The impact is too big. You can't simple ignore whether the galaxy:
Spoiler – ME3 endings A) Has no more organics, because everyone turned into "cyborgs".
B) Has Reapers all over the place protecting and rebuilding.
C) Has no more AIs as they were all destroyed.
There's simply no way to ignore that. It's three completely different versions of the galaxy.