about to start playing - what to do with motb?

Hi all,

I'm about to start playing NWN2. It's been on the shelf for awhile so I thought I better have a go!

Should I install mask of the betrayer now? Will any of the new content (or features) be available to me from the start or do I have to complete the original game quest first? Does having motb override the need for existing game patches (e.g. 1.10)?

Thanks!
Dray.