I remember having a heck of a time with that fight, largely because I didn't really understand the battle. Checking a game guide helped me out a ton.
You should experiment with all of the camera modes in the game. I remember having a very hard time with battles at first, mostly because I didn't know exactly where to click. Experiment a bit and you'll do fine.
Also, check your save game directory every couple of nights. This game makes a LOT of auto-save files and, after several hours of play, the save files get huge. They can fill up your hard drive fast.
Edit: Oh yeah, and the in-game music IS great! I especially liked the music at the docks. If you have
Irfanview with all its plug-ins, you can play that music back any time.
Does anyone actually use those secondary weapons? When I went through the game (on medium difficulty), I never used them.