Here are some details about the recently announced Dead Space 2.
http://www.ggmania.com/?smsid=28235
* The opening of the game finds Isaac on a space station, The Sprawl, along with the Marker.
* You get to witness the start of the infection on The Sprawl
* Isaac will speak in this one.
* Isaac will interact with other NPC's in Dead Space 2.
* Isaac will continue suffering from mild dimentia as a result of his interaction with the Marker in the first game.
* Largely similar graphics but slightly updated and refined.
http://www.ggmania.com/?smsid=28235