I ended up with about 82 toughness - and I still ltook heavy damage from Soul Eaters and the like. I was playing on 'normal' then switched to hard near the end, because it wasn't very challenging (even for me). What I did find though was that armour made a huge difference - I played a demon hunter and the shield ability you get meant I took essentially 0 damage from almost everything, except shadow lords, by the end of the game. Even with lower toughness. But as soon as that shield wore off I was pretty badly battered about, especially with constant mobs and interripted attack routines, as in Skull island finale. By the way, the last boss fight, while way better than the end of Risen 1, was irritating - too many targets, hitting wrong thing too often, having to bounce around like a yo-yo to avoid attacks. Just too much. I did not enjoy it. I should say I had way less impressive stats and abilities than some people have reported here by that point - nothing about 85, no really fancy items crafted etc. So maybe I wasn't well enough prepared. I can also confirm that blade dancer is indispensible and makes a world of difference. I'd be curious to see a playthrough without such 'unbalancing' abilities...