One of the cooler features we saw today was the new cybernetic system. Throughout the course of the game, Seth will face greater and greater challenges and it's likely that the player will be tempted to use cybernetic implants just to stay competitive. You may begin by simply replacing an eye to get better skill with your weapons, but once you start down the road of cybernetics, you probably won't stop until you've rebuilt your entire body from head to toe. And since the implants are permanent, you'll need to question whether or not you really want to sacrifice your humanity just to gain an edge on the competition.
Gas Powered Games indicated that the morale conflict between needing better performance and not wanting to sacrifice your humanity will play a part in your discussions with other characters and will even alter the game's ending based on how much or how little you altered your body. Players who refuse to use implants will be at a definite disadvantage, but they will have access to a couple of high level skills towards the end of the game that are off-limits to cybernetic characters.