Farflame
SasqWatch
It's even more likely that humanity wouldn't be human. I would hope genetic engineering would oust most genetic diseases in the next century.
Probably only for the most wealthy class. They already have elite schools for their kids and a lot of media / political / secret service puppets… etc.
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Another game
Anyway I found out that sci-fi Dark Souls clone Dolmen is surprisingly another one that meets the criteria.
Description:
As an explorer, you’ve been ASLEEP for quite some time. Your memory is somewhat of a blur, your background isn’t very well known. You have to find out why these insect-like creatures have taken over the mining colony