GameWatcher interviewed Florent Guillaume about Vampyr at the E3:

Vampyr: An Interview With DONTNOD Entertainment’s Florent Guillaume [E3 2017]

Being a doctor can’t be an easy life. You are responsible for the health and well-being of the sick people you vow to help cure. However, what if the same people you wanted to protect were also the only thing that could sustain your life? That’s where Doctor Jonathan Reed finds himself in early 19th Century London in Focus Home Interactive and DONTNOD Entertainment’s upcoming role-playing game, Vampyr. Reed has become a vampire, and he must split himself between his vow to help the sick and his need to feed on the blood of those he swore to protect.

Dr. Acula jokes aside, Vampyr contains a story with a vast web of interaction and consequences. Who you save and who you feed upon will not just affect you, but the people around that person. To help untangle this web of intrigue, GameWatcher caught up to DONTNOD’s Lead Level Designer Florent Guillaume at E3 to guide us into the life of this doctor in a vampire’s world. He took us through the dark corners of London to find out what kind of man Jonathan Reed is, how players will choose between doctor and vampire, and what consequences those choices will have for the fall or salvation of London in Vampyr.

GameWatcher: Where do we find ourselves starting off in Vampyr? Who is Jonathan Reed?

Florent Guillaume: So you start Vampyr waking up in a mass grave, and quickly find you’ve been afflicted with vampirism. You’ve been transformed. The game is set in London in 1918. Reed is a doctor that was fighting in France during World War I as a combat medic and doctor. When he returns home, his journey takes an unfortunate turn and that’s when he is transformed.

[...]

Thanks Farflame!