"Chalk up another for The Maniac!"
The Maniac… from one of those Wing Commander games
"Let me kill the meatbags, master!"
HK-47 in Knights of the Old Republic
"Magic is OK but now Minsc leads! Swords for everybody!"
Baldur's Gate (2?)
"The parasites say 'Noooo!'"
Andrew Ryan in BioShock 2 (actually, quite a few things he said)
"You've been a slave to your employees for too long, shouldn't it be the other way around?"
Advertisement for EndetureTech in Mass Effect 2
"No tests on species who's members capable of calculus. Simple rule: never broke it."
Mordrin - Mass Effect 2
"I
talk to people, you know? Ask them if they have big problems that only I can solve! You'd be surprised how many people are just waiting for someone to talk to them. <pause> Sometimes I poke through crates, too - you know - for extra credits."
Conrad - Mass Effect 2
And, of course, Cave Johnson's recent tirade about
lemons.