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GameFront has a small list of mods for The Witcher, most of which we've covered before. Thatsaid, Roxtar's Extreme Immersion Mod is an interesting idea if you've already played the game through a few times:
More information.The Witcher Extreme Immersion Mod is not for the faint of heart. Modder Roxtar stripped almost all of the HUD elements out leaving the player to rely on observations and wits alone. Geralt’s stance is the only indication of which fighting style he’s taking and your enemy’s wounds are the only health bar you get. For a more detailed description of The Witcher Extreme Immersion Mod, check out Roxtar’s post on The Witcher Enhanced Edition Forum.