Quick PC specific observations:
Performance is extremely smooth - but I'm using a 1080 ti. But it's so smooth that I think the game will run just fine even on mediocre hardware. Played for an hour or so - and there's been absolutely no sign of slowdown anywhere.
Controls are vastly superior on PC. In fact, I worry the game might be too easy on Nightmare - but I won't know until later. But they're fast and super responsive.
Unexpectedly, there's no HUD customization beyond removing tutorial prompts. Can't say it bothers me at all, but I know we have some HUD purists around here - and they'll likely be annoyed at this.
Quick save is instant - and quick load is instant too, unless you load from another area, but it's still very fast.
Not a fan of chromatic aberration on text in books and tablets.
Still not sold on the art style. The late 60s luxury vibe feels strangely out of place. It's giving me a strange sort of 2001 + 2010 vibe (the movies).
Gameplay remains extremely satisfying for me, but I'm a big fan of System Shock 2 - and this is very clearly a spiritual successor. They spell it out for you in various ways, and you'll know what I mean when you play it.
Love how the toilet seat is down when you play the female version of Morgan