Denuvo already interferes with mods on certain games look at Just Cause 3. Anyway most games with Denuvo already include a program called Easy Anti-Cheat.Many big name Asian MMOs use anti cheat addons to prevent cheating and I remember some western mmos do too. But that is because they have microtransactions. If a game doesnt have that and has an initial cost to play, then denuvo is in the market for them. But that type of game is increasingly rare so…
Link - https://www.easy.ac/en-us/
It's a pain making trainers to cheat even in single-player with this program.